She was born Marilyn Louis on August 10, 1923 in Hollywood, California.
She was nicknamed the "Queen of Technicolor" because her fair complexion and flaming red hair photographed exceptionally well in Technicolor.
Rhonda made her first film appearance as an uncredited dance hall girl in 1943 in the film In Old Oklahoma.
She has appeared in over 40 films, including Spellbound (1945), Out of the Past (1947), Spiral Staircase (1946), A Connecticut Yankee in King Arthur's Court (1949), Gunfight at the O.K. Corral (1957), While the City Sleeps (1956) and The Big Circus (1959). Her most recent film was Waiting for the Wind in 1990.
During the 1950s and into the '60s, Fleming frequently appeared on television with guest-starring roles on The Red Skelton Show, The Investigators, The Dick Powell Show, Wagon Train, The Virginian, Police Woman, McMillan and Wife and the Love Boat.
In retirement, Fleming has worked for several charities, especially in the field of cancer care, and hsd served on the committees of many related organizations.